Dr. Chandi Charan Malakar

Associate Professor (Chemistry)

National Institute of Technology Manipur

Department of Chemistry

Langol, Imphal-795004

E-mail: [email protected], [email protected]

Tel: +91 9366605025

Language Skills:

English, German, Hindi, Bengali

Group Homepage

• https://scholar.google.co.in/citations?hl=en&user=fJa2tC4AAAAJ
• https://www.researchgate.net/profile/Chandi_Malakar
• https://www.scopus.com/authid/detail.uri?authorId=24069079200
• https://nitmanipur.irins.org/profile/132584
• https://www.webofscience.com/wos/author/record/C-7163-2017
  
• https://orcid.org/0000-0002-9478-017X
  
• Personal website:   http://chdeepm.wixsite.com/mysite

          Citations:   2255 (till May 2025)

          h-index:     25 (till May 2025)

          i10-index:  68 (till May 2025)

• List Publications: In International Journals 127; Book Chapters 11; Patents 6; Conference Paper Presentations 49
  

Journal Publications:

(1) E. Merisor, J. Conrad, C. C. Malakar and U. Beifuss “Unexpected Lewis acid mediated reactions of 1-arylbut-3-en-1-ols with trimethylorthoformate - A new synthesis of homoallyl ethers and chlorides” Synlett 2008, 903-907

(2) S. Adimurthy, C. C. Malakar and U. Beifuss “Influence of bases and ligands on the outcome of the Cu(I)-catalyzed oxidative homocoupling of terminal alkynes to 1,4-disubstituted 1,3-diynes using oxygen as an oxidant” J. Org. Chem. 2009, 74, 5648-5651, https://doi.org/10.1021/jo900246z.

(3) C. C. Malakar, E. Merisor, J. Conrad and U. Beifuss, “MoO₂Cl₂(dmf)₂ Catalyzed Domino Reactions of w-Nitro Alkenes to 3,4-Dihydro-2H-1,4-  benzothiazines and Other Heterocycles” Synlett 2010, 1766-1770, DOI: 10.1055/s-0030-1258119.

(4) C. C. Malakar, D. Schmidt, J. Conrad and U. Beifuss “Double C-H Activation: The Palladium-Catalyzed Direct C-Arylation of Xanthines with Arenes” Organic Letters 2011, 13, 1378-1381,   https://doi.org/10.1021/ol200065s

(5)  C. C. Malakar, D. Schmidt, J. Conrad and U. Beifuss “Cu(I)-Catalyzed Domino Reactions: Efficient and Selective Synthesis of 4H-Chromenes and Naphthalenes” Organic Letters 2011, 13, 1972-1975,  https://doi.org/10.1021/ol200347g

(6) C. C. Malakar, K. Sudheendran, H.-G. Imrich, S. Mika and U. Beifuss “Cu(I)-catalyzed annulation for the synthesis of substituted naphthalenes using o-bromobenzaldehydes and β-ketoesters as substrates” Org. Biomol. Chem., 2012, 10, 3899-3905 (Top ten most accessed article in April 2012), https://doi.org/10.1039/C2OB06963F

(7) C. C. Malakar, A. Baskakova, J. Conrad and U. Beifuss “Copper-Catalyzed Synthesis of Quinazolines in Water starting from o-Bromobenzylbromides and Benzamidines” Chem. Eur. J., 2012, 18, 8882-8885 (Highlighted in Sigma-Aldrich catalog 2013), https://doi.org/10.1002/chem.201200583

(8) N. Aljaar, C. C. Malakar, J. Conrad, S. Strobel, T. Schleid and U. Beifuss “Cu-Catalyzed Reaction of 1,2-Dihalobenzenes with 1,3-Cyclohexanediones for the Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones” J. Org. Chem. 2012, 77, 7793-7803, https://doi.org/10.1021/jo3014275

(9) K. Sudheendran, C. C. Malakar, J. Conrad and U. Beifuss “Copper(I)-Catalyzed Intramolecular O-Arylation for the Synthesis of 2,3,4,9-Tetrahydro-1H-xanthen-1-ones with Low Loads of CuCl” J. Org. Chem. 2012, 77, 10194-10210, https://doi.org/10.1021/jo3018318

(10) C. C. Malakar, B. U. W. Maes and K. A Tehrani “An In(III)-Catalyzed Synthesis of 4,4-Dichloro-1-aryl-N-alkyl-1-yn-3-amines via an Intermolecular C(sp²)-C(sp) Bond Formation” Adv. Synth. Catal.2012, 354, 3461-3467, http://dx.doi.org/10.1002/adsc.201200680

(11) C. C. Malakar, S. Stas, W. Herrebout and K. A Tehrani “Lewis acid Mediated Vinyl Transfer Reaction of Alkynes to N-Alkylimines using the N-Alkyl Residue as a Sacrificial Hydrogen Donor” Chem. Eur. J., 2013, 19, 14263–14270, https://doi.org/10.1002/chem.201300469

(12) N. Aljaar, C. C. Malakar, J. Conrad, W. Frey and U. Beifuss “The Reaction of 1-Nitroso-2-naphthols with alfa-Functionalized Ketones and Related Compounds-The Unexpected Formation of Decarbonylated 2-Substituted Naphtho[1,2-d][1,3]oxazoles” J. Org. Chem. 2013, 78, 154-166  (Highlighted in Sigma-Aldrich catalog 2013), https://doi.org/10.1021/jo3022956

(13) R. K. Devappa, C. C. Malakar, H. P. S. Makkar and K. Becker “Pharmaceutical Potential of Phorbol esters from Jatropha Curcas Oil” Nat. Prod. Res., 2013, 27, 1459-1462,   https://doi.org/10.1080/14786419.2012.716057 

(14) K. Sudheendran, C. C. Malakar, J. Conrad and U. Beifuss “Synthesis of Functionalized Naphthalenes by Copper(I)-Catalyzed Annulation between 3-(2-Halobenzyl)pentane-2,4-diones and β-Keto Esters, Malonates and Cyanoacetates” Adv. Synth. Catal. 2013, 355, 2400-2416, https://doi.org/10.1002/adsc.201300372

(15) A. H. Moustafa, C. C. Malakar, N. Aljaar, E. Merisor, J. Conrad and U. Beifuss “Microwave-assisted molybdenum-catalyzed reductive cyclization of o-nitrobenzylidene amines to 2-aryl-2H-indazoles” Synlett, 2013, 24, 1573-1577, DOI: 10.1055/s-0033-1339195

(16) D. Schmidt, C. C. Malakar and U. Beifuss “2,3-Dihalo-1-propenes as Building Blocks in Cu(I)-Catalyzed Domino Reactions: Efficient and Selective Synthesis of Furans” Organic Letters 2014,16, 4862-4865, https://doi.org/10.1021/ol502371j

(17) C. C. Malakar and G. Helmchen “Immobilized Catalyst for Iridium-Catalyzed Allylic Amination – Rate Enhancement by Immobilization” Chem. Eur. J., 2015, 21,7127-7134 (Selected as a HOT paper / Selected for Front cover page picture / Recommended by publisher for a press release at University of Heidelberg, Germany and  (Highlighted in Sigma-Aldrich catalog 2015), https://doi.org/10.1002/chem.201500382

(18) K. Kushwaha, C. C. Malakar, S. Stas and K. A Tehrani “Indium(III)-Catalyzed Tandem Synthesis of 2-Alkynyl-3,3-dichloropyrrolidines via Addition/Cyclization of Alkynes to α,α,γ-Trichloroaldimines” RSC Advances 2015, 5, 10139-10151, https://doi.org/10.1039/C4RA14214D

(19) N. Aljaar, C. C. Malakar, J. Conrad and U. Beifuss “Base-Promoted Domino Reaction of 5-Substituted 2-Nitrosophenols with Bromomethyl Aryl Ketones: A Transition Metal-free Approach to 2-Ketoaryl Benzoxazoles” J. Org. Chem. 2015, 80, 10829-10837, https://doi.org/10.1021/acs.joc.5b02000

(20) K. Seehafer, C. C. Malakar, J. Qu and G. Helmchen “Iridium-Catalyzed Allylic Substitutions with Bulky Amines – an Entry into the Reetz Synthesis of Aminoalcohols” Eur. J. Org. Chem. 2016, 2016, 493-501, https://doi.org/10.1002/ejoc.201501333

(21) K. Kushwaha, B. Pinter, S. A. Shehzadi, C. M. L. Vande Velde, F. de Proft,C. C. Malakar, and K. A Tehrani “Metal-free synthesis of chlorinated β-amino ketones via an unexpected reaction of imines with arylacetylenes in 1,1,1,3,3,3-hexafluoro-2-propanol”Adv. Synth. Catal. 2016, 358, 41-49, https://doi.org/10.1002/adsc.201500519

Publications from NIT Manipur (2016 – present)

(22) N. Vodnala, D. Kaldhi, S. Polina, V.P. R. K. Putta, R. Gupta, S. C. P. Promily, R. K. Linthoinganbi, V.     Singh, C. C. Malakar “Pd-Catalyzed Domino Reactions of Nitroaromatics: A Surrogate Access towards the Saturated N-heterocycles” Tetrahedron Lett., 2016, 57, 5695-5699, https://doi.org/10.1016/j.tetlet.2016.11.037

(23) N. Vodnala, D. Kaldhi, R. Gupta, S. Polina, V.P. R. K. Putta, S. C. P. Promily, R. K. Linthoinganbi, V.     Singh, C. C. Malakar “Novel Domino Routes for the Synthesis of N-Heterocycles via Reductive Cyclization of β-(N-2-Nitroaryl)-α,β-unsaturated Ketones” ChemistrySelect 2016, 1, 5784-5788, https://doi.org/10.1002/slct.201601221

(24) N. Devi, D. Singh, R. K. Sunkaria, C. C. Malakar, S. Mehra, R. K. Rawal, V. Singh “An In(OTf)₃-HBF₄ assisted multicomponent approach for one-pot synthesis of pyrrazolopyridinone fused imidazopyridines” ChemistrySelect 2016, 1, 4696-4703,   https://doi.org/10.1002/slct.201601133

(25) D. Singh, N. Devi, V. Kumar, C. C. Malakar, S. Mehra, S. Rattan, R. K. Rawal, V. Singh “Natural products inspired design and synthesis of beta-carboline and gama-lactone based molecular hybrid” Org. Biomol. Chem. 2016, 14, 8154 –8166, https://doi.org/10.1039/C6OB01216G

(26) D. Singh, N. Devi, V. Kumar, C. C. Malakar, S. Mehra, R. K. Rawal, B. S. Kaith, V. Singh “A metal free 1,3-dipolar cycloaddition approach towards regioselective synthesis of beta-carboline and isoxazole based molecular hybrid” RSC Adv., 2016, 6, 88066-88076, https://doi.org/10.1039/C6RA15875G

(27) N. Devi, D. Singh, G. Kaur, S. Mor, V. P. R. K. Putta, S. Polina, C. C. Malakar, V. Singh “In(OTf)₃ – assisted synthesis of beta-carboline-C3-tethered imidazo[1,2-a]azine derivatives” New J. Chem.2017, 41, 1082-1093, https://doi.org/10.1039/C6NJ03210A

(28) D. Singh, V. Kumar, N. Devi, C. C. Malakar, R. Shankar, V. Singh “Metal-free decarboxylative amination: An alternative approach towards regioselective synthesis of beta-carboline-N-fused imidazoles” Adv. Synth. Catal. 2017, 359, 1213-1226, https://doi.org/10.1002/adsc.201600970

(29) K. Mukherjee,R. S. Dey,C. C. Malakar, B. Pal “A Special Section on Functional Materials for Energy and Environment: Progress and Perspective” Energy & Environment Focus, 2017, 6, 49-51, https://doi.org/10.1166/eef.2017.1244

(30) D. Singh, P. Sharma, R. Kumar, S. K. Pandey, C. C. Malakar and V. Singh, “An Expeditious Approach for the Synthesis of β-Carboline-Pyrazole-Based Molecular Hybrids” Asian J. Org. Chem. 2018, 7, 383-394, https://doi.org/10.1002/ajoc.201700545

(31) V. Kumar, S. Chaudhary, M. Mathur, A. K. Swami, C. C. Malakar and V. Singh, “A Tandem Approach towards Diastereoselective Synthesis of Quinoline C-3 Tethered γ-Lactones” ChemistrySelect 2018, 3, 399-404, https://doi.org/10.1002/slct.201702923

(32)  V. P. R. K. Putta, R. Gujjarappa, N. Vodnala, R. Gupta, P. P. Pujar and C. C. Malakar “The facile and efficient organocatalytic platform for accessing 1,2,4-selenadiazoles and thiadiazoles under aerobic conditions” Tetrahedron Lett. 2018, 59, 904-908, https://doi.org/10.1016/j.tetlet.2018.01.063

(33) D. Singh, C. K. Hazra, C. C. Malakar, S. K. Pandey, B. S. Kaith and V. Singh “Indium-Mediated Domino Allylation-Lactonisation Approach: Diastereoselective Synthesis of β-Carboline C-3 Tethered α-Methylene γ-Butyrolactones” ChemistrySelect 2018, 3, 4859-4864, https://doi.org/10.1002/slct.201800006

(34) R. Gujjarappa, N. Vodnala, A. K. Kabi, D. Kaldhi, M. Kumar, U. Beifuss and C. C. Malakar “Efficient Syntheses of Diverse N-Heterocycles: The Molybdenum(VI)-Catalyzed Reductive Cyclization of Nitroarenes using Pinacol as a Deoxygenating Agent” SynOpen 2018, 2, 138-144, http://dx.doi.org/10.1055/s-0036-1591572.

(35) N. Vodnala, R. Gujjarappa, A. K. Kabi, M. Kumar, U. Beifuss and C. C. Malakar “Facile Protocols towards C2-Arylated Benzoxazoles using Fe(III)-Catalyzed C(sp²-H) Functionalization and Metal-Free Domino Approach” Synlett 2018, 29, 1469-1478, http://dx.doi.org/10.1055/s-0037-1609718.

(36) R. Gujjarappa, S. K. Maity, C. K. Hazra, N. Vodnala, S. Dhiman, A. Kumar, U. Beifuss and C. C. Malakar “Divergent Synthesis of Quinazolines using Organocatalytic Domino Strategies under Aerobic Conditions” Eur. J. Org Chem. 2018, 4628-4638, https://doi.org/10.1002/ejoc.201800746.

(37) N. Vodnala, R. Gujjarappa, C. K. Hazra, D. Kaldhi, A. K. Kabi, U. Beifuss and C. C. Malakar “Copper-Catalyzed Site-Selective Oxidative C-C Bond Cleavage of Simple Ketones for the Synthesis of Anilides and Paracetamol” Adv. Synth. Catal. 2019, 361, 135-145, https://doi.org/10.1002/adsc.201801096.

(38) D. Kaldhi, N. Vodnala, R. Gujjarappa, S. Nayak, V. Ravichandiran, S. Gupta, C. K. Hazra and C. C. Malakar “Organocatalytic Oxidative Synthesis of C2-Functionalized Benzoxazoles, Naphthoxazoles, Benzothiazoles and Benzimidazoles” Tetrahedron Lett. 2019, 60, 223-229, https://doi.org/10.1016/j.tetlet.2018.12.017

(39) V. P. R. K. Putta, R. Gujjarappa, U. Tyagi, P. P. Pujar and C. C. Malakar “A metal- and base-free domino protocol for the synthesis of 1,3-benzoselenazines, 1,3-benzothiazines and related scaffolds” Org. Biomol. Chem.2019, 17, 2516-2528, https://doi.org/10.1039/C8OB03058H

(40) R. Gujjarappa, N. Vodnala, M. Kumar and C. C. Malakar “Pd-Catalyzed Decarboxylation and Dual C(sp³)–H Functionalization Protocols for the Synthesis of 2,4-Diarylpyridines” J. Org. Chem. 2019, 84, 5005-5020, https://doi.org/10.1021/acs.joc.8b02971

(41) D. Singh, V. Kumar, C. C. Malakar and V. Singh “Structural Diversity Attributed by Aza-Diels-Alder Reaction in Synthesis of Diverse Quinoline Scaffolds” Curr. Org. Chem. 2019, 23, 920-958, http://dx.doi.org/10.2174/1385272823666190423140805

(42) N. Aljaar, R. Gujjarappa, M. Al-refai, M. Shtaiwi and C. C. Malakar “Overview on Recent Approaches towards Synthesis of 2-Keto-annulated Oxazole Derivatives” J. Heterocycl. Chem. 2019, 56, 2730-2743, https://doi.org/10.1002/jhet.3673

(43) D. Kaldhi, R. Gujjarappa, N. Vodnala, A. K. Kabi, N. Aljaar and C. C. Malakar “Mo(VI)-Catalyzed Synthesis of 2-Aryl-2H-Indazoles Using Pinacol Mediated Deoxygenation of Nitroaromatics” Chem. Lett. 2019, 48, 1258-1261, https://doi.org/10.1246/cl.190490

(44) V. P. R. K. Putta, N. Vodnala, R. Gujjarappa, U. Tyagi, A. Garg, S. Gupta, P. P. Pujar and C. C. Malakar “Reagent-Controlled Divergent Synthesis of 2-Amino-1,3-Benzoxazines and 2-Amino-1,3-Benzothiazines” J. Org. Chem. 2020, 85, 380-396. (Highlighted in Organic Chemistry Portal 2020, https://www.organic-chemistry.org/abstracts/lit7/128.shtm).

(45) R. Gujjarappa, N. Vodnala and C. C. Malakar “Decarboxylative cyclization of amino acids towards the Regioselective synthesis of 2,4-diarylpyridines via relay Fe(III)/In(III)-catalysis” Tetrahedron Lett. 2020, 61, 151495, https://doi.org/10.1016/j.tetlet.2019.151495

(46) R. Gujjarappa, N. Vodnala, V. P. R. K. Putta, V. G. Reddy and C. C. Malakar “Conversion of Alkynes into 1,2-Diketones using HFIP as Sacrificial Hydrogen Donor and DMSO as Dihydroxylating Agent” Tetrahedron Lett. 2020, 61, 151588, https://doi.org/10.1016/j.tetlet.2019.151588

(47) R. Gujjarappa, N. Vodnala, V. G. Reddy and C. C. Malakar “Niacin as a Potent Organocatalyst towards the Synthesis of Quinazolines using Nitriles as C-N Source” Eur. J. Org Chem. 2020, 803-814. (Highlighted in Chemistry Views 2020, https://www.chemistryviews.org/details/ezine/11218877/Organocatalyzed_Synthesis_of_Quinazolines.html).  https://doi.org/10.1002/ejoc.201901651

(48) R. Gujjarappa, N. Vodnala, A. Garg, C. K. Hazra, S. Gupta and C. C. Malakar “Amino Acid-Mediated Aerobic Oxidation of Organoborons for the Synthesis of Phenolic Derivatives using Single Electron Transfer” ChemistrySelect 2020, 5, 2419-2423, https://doi.org/10.1002/slct.201904059

(49) D. Kaldhi, N. Vodnala, R. Gujjarappa, A. K. Kabi, S. Nayak and C. C. Malakar “Transition-Metal-Free Variant of Glaser- and Cadiot-Chodkiewicz-Type Coupling: Benign Access to Diverse 1,3-Diynes and Related Molecules” Tetrahedron Lett. 2020, 61, 151775, https://doi.org/10.1016/j.tetlet.2020.151775

(50) N. Vodnala, R. Gujjarappa, V. Satheesh, R. Gupta, D. Kaldhi, A. K. Kabi and C. C. Malakar “Copper-Catalyzed [2+2+1+1] Annulation for the Regioselective Synthesis of 2,6-Diarylpyridines via C1-Insertion and Subsequent Cyclization” ChemistrySelect 2020, 5, 10144-10148, https://doi.org/10.1002/slct.202002968.

(51) R. Gujjarappa, N. Vodnala and C. C. Malakar “Recent Advances in Pyridine-Based Organocatalysis and its Application towards Valuable Chemical Transformations” ChemistrySelect 2020, 5, 8745-8758, https://doi.org/10.1002/slct.202002765.

(52) R. Gujjarappa, N. Vodnala and C. C. Malakar “Comprehensive Strategies for the Synthesis of Isoquinolines: Progress Since 2008” Adv. Synth. Catal. 2020, 362, 4896-4990, https://doi.org/10.1002/adsc.202000658.

(53) R. Gujjarappa, N. Vodnala, V. G. Reddy and C. C. Malakar “A Facile C-H Insertion Strategy using the Combination of HFIP and Isocyanides: The Metal-Free Access of Azole Derivatives” Asian J. Org Chem. 2020, 9, 1793-1797, https://doi.org/10.1002/ajoc.202000481.

(54) A. K. Kabi, R. Gujjarappa, N. Vodnala, D. Kaldhi, U. Tyagi, K. Mukherjee and C. C. Malakar “HFIP-Mediated Strategy towards β-Oxo Amides and Subsequent Friedel-Craft Type Cyclization to 2- Quinolinones using Recyclable Catalyst” Tetrahedron Lett. 2020, 61, 152535, https://doi.org/10.1016/j.tetlet.2020.152535.

(55) S. Sharma, C. C. Malakar, V. Singh “Transition-Metal-Free C-S Bond Forming Strategy towards Synthesis of Highly Diverse Pyrazole Tethered Benzothiazoles: Investigation of their Photophysical Properties” Asian J. Org Chem. 2020, 9, 1857-1868, https://doi.org/10.1002/ajoc.202000390

(56) N. Vodnala, R. Gujjarappa, S. Polina, N. Vodnala, V. Satheesh, D. Kaldhi, A. K. Kabi and C. C. Malakar “Organocatalytic C-C Bond Cleavage Approach: A Metal-Free and Peroxide-Free Facile Method for the Synthesis of Amide Derivatives” New. J. Chem. 2020, 44, 20940-20944, https://doi.org/10.1039/D0NJ04158K.

(57) S. Polina, V. P. R. K. Putta, R. Gujjarappa, V. Singh, P. P. Pujar and C. C. Malakar “P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds” Adv. Synth. Catal. 2021, 363, 431-445, https://doi.org/10.1002/adsc.202001149

(58) S. Polina, V. P. R. K. Putta, R. Gujjarappa, P. Pujar and C. C. Malakar “Aza-Michael addition of 1,2-diazoles to structurally diverse enones: Efficient methods toward β-amino ketones” J. Heterocycl. Chem. 2021, 58, 1029-1033, https://doi.org/10.1002/jhet.4221.

(59) V. Kumar, D. Singh, R. Gujjarappa, C. C. Malakar and V. Singh “Efficient Approach towards the Polysubstituted 4H-Pyran Hybrid Quinolone Derivatives and Subsequent Copper-Catalyzed Hydroxylation of Haloarenes” HeteroCycles 2021, 102, 465-479, https://doi.org/10.3987/COM-20-14383.

(60) N. Devi, A. Gupta, R. Gujjarappa, C. C. Malakar and V. Singh “Synthesis of Substituted Pyrazolo[4,3-c]quinolones and the C-C Bond Cleavage During Reductive Cyclization” HeteroCycles 2021, 102, 705-722, https://doi.org/10.3987/com-20-14403

(61) S. Kumar, C. C. Malakar and V. Singh “Cu(II)-Catalysed Azide-Alkyne Cycloaddition Reaction towards Synthesis of β-Carboline C1-Tethered 1,2,3-Triazole Derivatives” ChemistrySelect 2021, 6, 4005-4010, https://doi.org/10.1002/slct.202100002.

(62) R. Gujjarappa, N. Vodnala, A. Kandpal, L. Roy, S. Gupta, and C. C. Malakar “C_sp-C_sp Bond Cleavage and Fragments Coupling: Transition Metal-Free “Extrusion and Recombination” Approach towards Synthesis of 1,2-Diketones”  Org. Chem. Front., 2021, 8, 5389-5396, https://doi.org/10.1039/D1QO00848J.

(63) A. K. Kabi, R. Gujjarappa, A. Roy, A. Sahoo, D. Musib, N. Vodnala, V. Singh, and C. C. Malakar “Transition Metal-Free Transfer Hydrogenative Cascade Reaction of Nitroarenes with Amines/Alcohols: Redox-Economical Access to Benzimidazoles” J. Org. Chem. 2021, 86, 14597-14607, https://doi.org/10.1021/acs.joc.1c01450.

(64) R. Gujjarappa, N. Vodnala, D. Musib, and C. C. Malakar “Organocatalytic Decarboxylation and Dual C(sp3)-H Bond Functionalization Toward Facile Access to Divergent 2,6-Diarylpyridines” Asian J. Org. Chem. 2022, 11, e202100627, https://doi.org/10.1002/ajoc.202100627.

(65) M. Singh, R. Jamra, A. K. Paul, C. C. Malakar, V. Singh “KI-assisted Sulfur Activation/Insertion/Denitration Strategy towards Dual C−S Bond Formation for One-pot Synthesis of β-Carboline-tethered 2-Acylbenzothiophenes” Asian J. Org. Chem. 2022, 11, e202100653, https://doi.org/10.1002/ajoc.202100653.

(66) A. Garg, K. Kant, K. K. Roy, A. Sahoo, C. C. Malakar, S. Gupta “Docking-based evaluation against Human Tankyrase-1 and Tankyrase-2 enzyme” Materialstoday: Proceedings. 2022, 57, 300-306, https://doi.org/10.1016/j.matpr.2022.03.095.

(67) R. Reetu, A. Garg, K. K. Roy, A. Roy, S. Gupta, C. C. Malakar “In-silico studies for targeting PPARγ for the Type II Diabetes Mellitus” Materialstoday: Proceedings. 2022, 57, 44-48, https://doi.org/10.1016/j.matpr.2022.01.299.

(68) R. Reetu, R. Gujjarappa, C. C. Malakar “Recent Advances in Synthesis and Medicinal Evaluation of 1,2-Benzothiazine Analogues” Asian J. Org. Chem. 2022, 11, e202200163,  https://doi.org/10.1002/ajoc.202200163.

(69) E. P. Devi, D. Kaldhi, R. Sengupta, A. Roy, A. Sahoo, I. Saha, C. C. Malakar “Catalytic Iodine and Morpholine as Reagent Combination for Hydration of Alkynes via Markovnikov Addition” Asian J. Chem. 2022, 34, 1592-1596, https://doi.org/10.14233/ajchem.2022.23751.

(70) L. S. Singh, A. K. Kabi, R. Sengupta, A. Roy, A. Sahoo, I. Saha, C. C. Malakar “C-H Functionalization and C-N Bond Formation Approaches under Catalytic Conditions for the Synthesis of α-Ketoamides and 2,4-Disubstituted-1,3,5-triazines” Asian J. Chem. 2022, 34, 1841-1847, https://doi.org/10.14233/ajchem.2022.23769.

(71) P. S. Kishore, R. Gujjarappa, R. K. Putta, S. Polina, V. Singh, P. P. Pujar, C. C. Malakar “Potassium tert-Butoxide-Mediated Synthesis of 2-Aminoquinolines from Alkylnitriles and 2-Aminobenzaldehyde Derivatives” ChemistrySelect 2022, 7, e202204238, http://dx.doi.org/10.1002/slct.202204238.

(72) V.P. R. K. Putta, S. Polina, R. Gujjarappa, P. S. Kishore, C. C. Malakar, P. P. Pujar “Efficient Synthesis of 4H-3,1-Benzothiazin-4-ones via C-N/C-S Bond Forming Reactions” Polycyl. Arom. Comp. 2023, 43, 7416-7425, https://doi.org/10.1080/10406638.2022.2136220.

(73) L. S. Singh, S. Banerjee, I. Saha, C. C. Malakar “Organocatalyzed-Aerobic Oxidation of Arylboronic Acids toward the Synthesis of Phenolic Derivatives” Lett. Org. Chem. 2023, 20, 533-540, http://dx.doi.org/10.2174/1570178620666221128121925.

(74) Vaishali, C. C. Malakar, V. Singh “A Cascade A3 Coupling Strategy towards Regioselective Synthesis of β-Carboline N-fused Pyrrole Derivatives with Pyridine Tethers” New J. Chem. 2023, 47, 1186-1196, https://doi.org/10.1039/D2NJ04620B.

(75) C. C. Malakar, L. Dell'Amico, W. Zhang “Dual Catalysis in Organic Synthesis: Current Challenges and New Trends” Eur. J. Org. Chem. 2023, 26, e202201114, https://doi.org/10.1002/ejoc.202201114.

(76) S. Sharma, D. Singh, S. Kumar, R. Jamra, N. Banyal, Deepika, C. C. Malakar, V. Singh “An Efficient Metal-free and Catalyst-free C-S/C-O Bond Formation Strategy: Synthesis of Pyrazole Conjugated Thioamides and Amides”   Beilstein J. Org. Chem. 2023, 19, 231-244, https://doi.org/10.3762/bjoc.19.22.

(77) A. K. Kabi, M. Pal, R. Gujjarappa, C. C. Malakar, Mithun Roy “Overview of Hydroxychloroquine and Remdesivir on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)” J. Heterocycl. Chem. 2023, 60, 165-182, https://onlinelibrary.wiley.com/doi/full/10.1002/jhet.4541.

(78) M. Shtaiwi, M. Al-Refa'I, L. Al-Najjar, N. Al-jaar, C. C. Malakar, A. Shtaiwi, M. A. Sini “Design, Synthesis, Biological Activity, and Molecular Modeling of Novel Spiroquinazoline Derivatives as Acetylcholinesterase Inhibitors for Alzheimer Disease” Polycyl. Arom. Comp. 2023, 43, 8082-8095, http://dx.doi.org/10.1080/10406638.2022.2144911.

(79) K. Kant, S. Banerjee, C. K. Patel, S. Kalita, R. Reetu, P. Nayak, N. Al-Jaar, C. C. Malakar “Advances on Catalytic Approaches towards the Synthesis of Quinoline Derivatives using Povarov Reaction” Heterocycles 2023, 106, 925-967, http://dx.doi.org/10.3987/REV-23-1004.

(80) N. Al-jaar, M. M. Ibrahim, E. A. Younes, M. Al-Noaimi, K. A. Abu-Safieh, B. F. Ali, K. Kant, C. C. Malakar,  “Strategies towards the Synthesis of 2-Ketoaryl Azole Derivatives using C-H Functionalization Approach and 1,2-Bis-Nucleophile Precursors” Asian J. Org. Chem. 2023, 12, e202300036, https://doi.org/10.1002/ajoc.202300036.

(81) E. Pinky Devi, S. Polina, K. Kant, A. K. Kabi, N. Al-Zaqri, N. Aljaar, C. C. Malakar “N-Alkylation of Azoles with Enones Assisted by P(III) or Fe₂O₃-nanoparticles as Recyclable Catalyst” Heterocycles 2023, 106, 1023-1038, https://doi.org/10.3987/COM-23-14833.

(82) C. K. Patel,  R. Gujjarappa,  K. Kant,  S. Ghanta, V. Singh, A. K. Kabi, N. Al-Zaqri,  C. C. Malakar “Copper-Catalyzed C(sp³)−Functionalization and Annulation of 2-Bromoaryl Oximes with Active Methylene Compounds towards Synthesis of Isoquinoline N-Oxides”    Adv. Synth. Catal. 2023, 365, 2203-2210, https://doi.org/10.1002/adsc.202300217.

(83) M. Singh, Deepika, S. Kumar, Jyoti, N. Kumar, B. Bhudalkoti, C. C. Malakar, V. Singh “Transition Metal-free Cascade C-N Bond Formation: An Effective Strategy for the Synthesis of β-Carboline N-Fused Imidazolium Acetates and Estimation of their Light Emitting Properties” Synthesis 2023, 55, 3329-3341, 10.1055/s-0041-1738447.

(84) S. Kumar, R. Kumar, C. C. Malakar, V. Singh “Copper catalysed regioselective synthesis of pyrimidine substituted Indolizino[8,7-b]indole derivatives via cascade A3 annulation” Tetrahedron 2023, 142, 133547, https://doi.org/10.1016/j.tet.2023.133547.

(85) D. Dhillon, A. K. Paul, C. C. Malakar, A. Bansal, V. Singh “DABCO Mediated Sulfur Activation-Intramolecular De-nitration Strategy for the Synthesis of Novel Dihydrothiochromeno[4,3-c]pyrazoles” Asian J. Org. Chem. 2023, 12, e202300289, https://doi.org/10.1002/ajoc.202300289.

(86) C. K. Patel, S. Banerjee, K. Kant, R. Sengupta, N. Aljaar, C. C. Malakar “Roles of Alkali Metals tert-Butoxide as Catalysts and Activators in Organic Transformations” Asian J. Org. Chem. 2023, 12, e202300311, https://doi.org/10.1002/ajoc.202300311.

(87) Y. A Teli, R. Reetu, P. G. Singh, M. J. Patel, S. Dash, S. Paine, P. S. Prabhakar, V. Singh, K. S Keremane, N. Al-Zaqri, K. Mukherjee, S. Dutta, C. C. Malakar “Synthesis and Characterization of Novel Pd@rGO−CuFe₂O₄ Magnetic Nanoparticles: A Recyclable Catalyst for C−C Coupling Reaction in Biomass-Derived Organic Solvent”   Asian J. Org. Chem. 2023, 12, e202300481, https://doi.org/10.1002/ajoc.202300481. 

(88) K. Kant, C. K Patel, S. Banerjee, P. Naik, A. K Atta, A. K Kabi, C. C. Malakar “Recent Advancements in Strategies for the Synthesis of Imidazoles, Thiazoles, Oxazoles, and Benzimidazoles” ChemistrySelect 2023, 8, e202303988, https://doi.org/10.1002/slct.202303988. 

(89) L. S. Singh, K. Kant, S. Banerjee, R. Sengupta, A. A AlObaid, M. Pal, S. Dutta, N. Aljaar, C. C. Malakar “The γ-Valerolactone (GVL) as Innoxious Reaction Media for the Synthesis of 2-Aryl-2H-Indazoles via C-N and N-N Bond Formation under Cu(I)-Catalyzed Ligand and Base Free Conditions” Polycyl. Arom. Comp.  2024, 44, 4832-4843, https://doi.org/10.1080/10406638.2023.2257846. 

(90) E. P. Devi, K. Kant, D. Kaldhi, S. Ghanta, R. Sengupta, N. Al-Zaqri, V. Singh, C. C. Malakar “Metal- and Hazardous Reagent-Free Transamidation Process: the NH₂OH-HCl Promoted N-Formylation and N-Acylation Reaction under Solvent-Less Conditions” Polycyl. Arom. Comp.  2024, 44, 4746-4758, https://doi.org/10.1080/10406638.2023.2257841. 

(91) R. Reetu, R. Gujjarappa, Y. A. Teli, M. J. Patel, S. Kalita, S. Dash, S. Ghanta, K. S Keremane, V. Singh, A. El-marghany, C. C. Malakar  “Transformation of Unactivated Alkenes into Iodohydrins and β-Iodoethers using Iodine-DMSO as a Reagent Combination” ChemistrySelect 2024, 9, e202304426, https://doi.org/10.1002/slct.202304426. 

(92) N. Banyal, C. C. Malakar, R. Kumar, V. Singh “DIPEA-Assisted Efficient One-Pot Three-Component Synthesis of Novel β-Carboline Tethered Pyran Derivatives” ChemistrySelect 2024, 9, e202304751, https://doi.org/10.1002/slct.202304751. 

(93) R. Reetu, S. Kalita, S. Dash, C. C. Malakar “Iodine and DMSO as Surrogate of Hazardous Metal and Non-Metal Reagents in Organic Synthesis” ChemistrySelect 2024, 9, e202303845, https://doi.org/10.1002/slct.202303845. 

(94) P. S. Kishore, R. Gujjarappa, M. J. Patel, S. Polina, VP R. K. Putta, V. Singh, C. C. Malakar, P. P. Pujar “A Metal-Free KO^tBu-Mediated Protocol towards the Synthesis of Quinolines, Indenoquinolines and Acridines” ChemistrySelect 2024, 9, e202304897, https://doi.org/10.1002/slct.202304897. 

(95) D. Singh, S. Sharma, R. K. Thakur, S. Nain, C. C. Malakar, Virender Singh “Cu-catalysed diversity-oriented synthesis of isoxazole and imidazo[1,2-a]azine conjugates” Tetrahedron 2024, 152, 133809, https://doi.org/10.1016/j.tet.2023.133809.

(96) Y. A. Teli, R. Reetu, R. Gujjarappa, S. Banerjee, S. Ghanta, M. J. Patel, V. Singh, N. Al-Zaqri, R. Sengupta, C. C. Malakar “B(OH)₃-Catalyzed Dual Friedel-Crafts Type Reaction of Anilines and Aldehydes to Access Di- or Triarylmethanes (TRAMs)” Eur. J. Org. Chem. 2024, 27, e202301086, https://doi.org/10.1002/ejoc.202301086.

(97) M. Shtaiwi, A. H. A. Sarhan, N. Aljaar, A. Shtaiwi, M. Abu-Sini, M. Alwahsh, L. Hamadneh, C. C. Malakar, K. A. Abu-Safieh “Enamino Barbiturates as Antiproliferative and Antimicrobial Agents: Studies on Synthesis, Biological Activities, and Molecular Modeling”  ChemistrySelect 2024, 9, e202400626, https://doi.org/10.1002/slct.202400626.

(98) N. Aljaar, H. F. Aboalrub, M. Shtaiwi, A. H. A. Sarhan, E. A. Younes, M. Al-Noaimi, A. Shtaiwi, L. H. Tahtamouni, K. A. Abu-Safieh, A. A. AlObaid, C. C. Malakar  “Cu-Catalyzed Synthesis of 4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones: Molecular Docking Studies and Anti-Proliferative Activities Against HepG2 Hepatocellular Carcinoma Cells” Asian J. Org. Chem. 2024, 13, e202400065, https://doi.org/10.1002/ajoc.202400065.

(99) N. Banyal, C. C. Malakar, R. Kumar, V. Singh “Transition Metal-Free Diastereoselective Synthesis of β-Carboline Tethered Dihydrofurocoumarin Derivatives” Asian J. Org. Chem. 2024, 13, e202300639, https://doi.org/10.1002/ajoc.202300639.

(100) N. Aljaar, M. Shtaiwi, B. F. Ali, M. Al-Refai, K. Kant, N. S. Bliss, M. Al-Noaimi, L. A. Al-Momani, C. C. Malakar “ortho-Halobenzyl Halides as Precursor for the Synthesis of Five- to Nine-Membered Ring Structures Employing Transition Metals as Catalysts”  Synthesis 2024, DOI: 10.1055/a-2311-4002.

(101) K. Kant, C. K. Patel, R. Reetu, Y. A. Teli, P. Naik, S. Some, C. K. Hazra, N. Aljaar, A. K. Atta, C. C. Malakar “Comprehensive Strategies on the Synthesis of Ene-Yne Derivatives” Synthesis 2024, DOI: 10.1055/a-2317-7262.

(102) A. K. Kabi, R. Gujjarappa, A. Garg, A. Sahoo, A. Roy, S. Gupta, C. C. Malakar “Biological Impacts of Imidazoline Derivatives”   Chemical Papers 2024,  78, 5743–5752, https://doi.org/10.1007/s11696-024-03496-1.

(103) C. K. Patel, K. Kant, Y. A. Teli, S. Banerjee, P. Naik, V. Sharma, K. S. Keremane, M. K. Al-Sadoon, V. Singh, C. C Malakar “Reductive C-N Bond Formation of Nitroarenes using Pd@rGO-CuFe₂O₄ Magnetic Nanoparticles in Water towards the Synthesis of N-Aryl Formamide and Azole Derivatives” Asian J. Org. Chem. 2024, 13, e202400255, https://doi.org/10.1002/ajoc.202400255.

(104) K. Kant, C. K. Patel, S. Banerjee, P. Naik, A. Padhi, V. Sharma, V. Singh, R. Almeer, K. S. Keremane, A. K. Atta, C. C Malakar “HFIP-Mediated Cyclodesulfurization Approach for the Synthesis of 2-Aminobenzoxazole and 2-Aminobenzothiazole Derivatives” Asian J. Org. Chem. 2024, 13, e202400223, https://doi.org/10.1002/ajoc.202400223.

(105) B. Dey, S. Ghosh, C. C. Malakar, A. K. Atta “Review on pyrene-based fluorometric chemosensing materials for picric acid and their AIE properties” Microchemical Journal, 2024, 200, 110486.

(106) Y. A. Teli, R. Reetu, S. A. Chanu, K. S. Keremane, R. Almeer, V. Singh, C. C. Malakar “HFIP-Mediated Dual C(Ar)-Alkylation Process towards the Regioselective Synthesis of Triarylmethanes (TRAMs)” Chemistry – An Asian J., 2024, https://doi.org/10.1002/asia.202400635

(107) C. K. Patel, K. Kant, S. Banerjee, S. Kalita, A. K. Atta, C. C. Malakar “Skeletal Editing Through Single Atom Insertion: An Insight into A New Era of Synthetic Organic Chemistry” Synthesis, 2024, DOI: 10.1055/a-2395-5804

(108) K. Kant, P. Naik, C. K. Patel, S. Some, S. Banerjee, A. Padhi, N. Aljaar, A. K. Atta, C. C. Malakar “Organocatalytic Approaches towards the Synthesis of Asymmetric Tetrahydroquinoline (THQ) Derivatives” Synthesis, 2024, DOI: 10.1055/a-2376-3524

(109) V. Kumar, S. Sharma, Vaishali, D. Singh, C. C. Malakar, Virender Singh “Exploration of Synthetic Potential of Quinoline-3-Carbaldehydes” Eur. J. Org. Chem., 2024, 27, e202400456.

(110) S. Ghosh, C. C. Malakar, P. Pahari, A. K. Atta “Amide/urea-based simple fluorometric receptors for iodide and Hg²⁺ ions in aqueous medium: Aggregation induced emission and DFT studies” Spectrochim. Acta A Mol. Biomol. Spectrosc. 2025, 325, 125134, https://doi.org/10.1016/j.saa.2024.125134.

(111) B. Dey, S. Ghosh, C. C. Malakar, A. K. Atta “Review on pyrene-based fluorometric chemosensing materials for picric acid and their AIE properties”  Microchem. J. 2024, 200, 110486, https://doi.org/10.1016/j.microc.2024.110486.  

(112) Vaishali, N. Banyal, S. Sharma, M. Singh, C. C. Malakar, V. Singh “An efficient, step-economical synthesis of β-carboline tethered imidazopyrido[3,4-b]indoles from acetals” New J. Chem. 2024, 48, 11394-11406.

(113) R. Jamra, C. C. Malakar, S. Khullar, V. Singh  “In(OTf)₃-catalysed A³-annulation strategy towards the synthesis of pyrazole-tethered quinoline derivatives and assessment of their luminescent properties”   New J. Chem. 2025, 19, DOI: https://doi.org/10.1039/D4NJ04130E.

(114) J. Jyoti, R. Jamra, D. Deepika, S. Sharma, C. C. Malakar, V. Singh “Regioselective Synthesis of Isocyano-containing Densely Functionalized Alkenes from Propynenitriles” Synlett. 2025, DOI: https://doi.org/10.1055/a-2538-1363

(115) K. Kant, P. Naik, Y. A. Teli, Jyoti, A. K. Kabi, V. Singh, N. Al-Zaqri, C. C. Malakar “TBAI-Promoted Electrochemical Cyclization: Synthesis of quinazolines using cascade C—N bond generation”    ChemistrySelect. 2025, 10, e202405092. DOI: https://doi.org/10.1002/slct.202405092

(116) V. Malakar, S. Dhanabal, B. Gowramma, A. Jangra, K. Kant, H. A. El-Serehy, K. S. Keremane, C. C. Malakar “Deciphering Potent Protein Tyrosine Phosphatase-1B Inhibitors Through In silico Molecular Docking, MMGBSA, and Molecular Dynamics” ChemistrySelect. 2025, 10, e202403082. DOI: https://doi.org/10.1002/slct.202403082

(117) K. Kant, P. Naik, C. K. Patel, T. A. Devi, Jyoti, A. K. Kabi, F. A. Al-Misned, V. Singh, C. C. Malakar “Electrochemical Cyclization–Desulfurization approach for the synthesis of 1,3-Benzoxazines using cascade C–O and C–N bond formation” J. Org. Chem. 2025, 90, 1835–1846. DOI: https://doi.org/10.1021/acs.joc.4c02429                                                                                                             

 (118) K. Kant, P. Naik, Jyoti, N. Aljaar, C. C. Malakar “Ionic Liquids in C-H Activation: Synthesis and Functionalization of Heterocycles and Carbocycles”   Org. Biomol. Chem., 2025, 23, 4260-4305. https://doi.org/10.1039/D4OB02109F.

(119) Y. A. Teli, K. Kant, S. A. Chanu, N. Aljaar, C. C. Malakar “Generation of C(sp³)-CAr Bonds in the Synthesis of Triarylmethanes (TRAMs): Comprehensive Progress Since 2009” Org. Biomol. Chem., 2025, 23, 3492-3519. https://doi.org/10.1039/D4OB02069C.

(120) A. Panwar, C. C. Malakar, A. Upadhyay, M. Roy “A red light-activable hetero-bimetallic [Fe(III)–Ru(II)] complex as a dual-modality PDT tool for anticancer therapy” Dalton Trans., 2025,54, 4474-4483.

(121) S. S. Ghosh, C. C. Malakar, P. P. Pahari, A. K. Atta “Amide/urea-based simple fluorometric receptors for iodide and Hg²⁺ ions in aqueous medium: Aggregation induced emission and DFT studies”  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125134.       

(122)     K. S. Keremane, M. G. Acharya, P. Naik, C. C. Malakar, K. Wang, B. Poudel “Recent Advances in Aggregation-Induced Emission (AIE) Fluorescent Sensors for Biomolecule Detection” Chemosensors 2025, 13, 174; https://doi.org/10.3390/chemosensors13050174.

(123) R. Bhowmik, M. Pal, N. Masarkar, S. Mukherjee, A. A. Singh, C. C. Malakar, M. Roy  “Synthesis, Protein-Binding Studies and Red Light-Assisted Cytotoxicity of Iron(III)-phenolato/Carboxylate Functionalized-Graphene Oxide and Single-Wall Carbon Nanotube” Chemistryselect 2025, 10, e202405855; https://doi.org/10.1002/slct.202405855.

(124) V. Kumar, K. Singh, S. Sharma, D. Singh, C. C. Malakar, Virender Singh “SnCl₂-mediated heterocyclization approach for the synthesis of benzisoxazole/quinoline-embedded β-carboline scaffolds” Org. Biomol. Chem., 2025, 23, 4782-4793. https://doi.org/10.1039/D5OB00299K.

(125) Jyoti, Vaishali, S. Sharma, D. P. Borthakur, Deepika, C. C. Malakar,  Virender Singh “A transition metal-free [3 + 2] cycloaddition approach for the efficient synthesis of trisubstituted pyrrole derivatives from β-chlorovinyl aldehydes” Org. Biomol. Chem., 2025, 23, 4735-4742. https://doi.org/10.1039/D5OB00351B.

(126) V. Malakar, S. P Dhanabal, A. Justin, D. Roy, K. Kant, R. Almeer, K. S. Keremane, C. C. Malakar   “Exploring the Multi-Target Effects of Valeriana officinalis in Alzheimer's Disease: a Network Pharmacology Approach” Chemistryselect 2025, 10, e202403078. https://doi.org/10.1002/slct.202403078.

(127) K. Kant, T. A. Devi, N. Nitin, C. C. Malakar “Role of Copper in Mechanochemical C-H activation Approaches: Mechanochemistry in C-C, C-X Bonds Formation” Asian J. Org. Chem. 2025, e202500139, https://doi.org/10.1002/ajoc.202500139.

Book Chapters:

(1) C. C. Malakar, R. Gujjarappa, N. Vodnala “Organocatalytic Process for the Synthesis of 2,6-Diaryl/Hetero-Aryl Pyridines” Indian Patent Application, Filed on 14^th June 2021, Application number: 202131026450. (Published in Indian Patent Office Official Journal, Issue no.30, 2022, page 47469). 

(2)  C. C. Malakar, D. Kaldhi, R. Gujjarappa “A Process for the Synthesis of Azides from Amines under Nitrite Salts-Free Approach” Indian Patent Application, Filed on 14^th September 2021, Application number: 202131041413. (Published in Indian Patent Office Official Journal, Issue no.30, 2022, page 47472).

(3) C. C. Malakar, D. Kaldhi, R. Gujjarappa “Process for the Nitrite Salt Free Preparation of Iodoarenes and Iodoalkanes” Indian Patent Application, Filed on 28^th October 2021, Application number: 202131049474 (Published in Indian Patent Office Official Journal, Issue no.7, 2022, page 9480).

(4)  C. C. Malakar, D. Kaldhi, R. Gujjarappa “Nitrite-Salts and Diazonium-Salts Free Process for the Preparation of Aryltriazole Derivatives” Indian Patent Application, Filed on 1^st August 2022, Application number: 202231043850. (Published in Indian Patent Office Official Journal, Issue no.31, 2022, page 49246).

(5)  M. Loya, A. K. Atta, C. C. Malakar,  “Bis-Pyrene Derivative Chemosensors for Quantifying Gold (III) Ions in Aqueous Medium and Process of Preparation Thereof” Indian Patent, Application number: 202331046716. Application date: 11.07.2023. (Published in Indian Patent Official Journal. Journal no. 35/2023, Vol. 4, date 01.09.2023, page no. 58089).

(6)  A. K. Atta, C. C. Malakar,  “Synthesis of Bis-Pyrene-Based Fluorometric Sensory Molecule and Method of Detection of Picric Acid Using Thereof” Indian Patent, Application number: .202431067756. Application date: 07.09.2024. (Published in the Patent Office Journal No. 37/2024, Dated 13/09/2024).

Papers Presented in Conferences: 

Papers presented in international conferences:

(1) E. Merisor, C. C. Malakarand U. Beifuss “Microwave assisted cyclization of ω-nitroalkenes: Synthesis of saturated N-heterocycles” GDCH Wissenschaftsforum Chemie 16-19 Sept. 2007, Universität Ulm (Germany).

(2) C. C. Malakar “New strategies for the transition metal-catalyzed synthesis and functionalization of

carbocycles and heterocycles” 15. TAG der ORGANISCHEN CHEMIE, Stuttgart, Germany, 14 October 2011.

(3) C. C. Malakar, K. Kushwaha, W. Herrebout, K. A. Tehrani “Lewis Acid Mediated Vinyl-Transfer Reaction of Alkynes to N-Alkylimines by Using the N-Alkyl Residue as a Sacrificial Hydrogen Donor” 17^th Sigma Aldrich meeting, 5-6 December 2013, Blankenberg, Belgium

Papers presented in national conferences:

 (4) C. C. Malakar “Application of Transition metal-catalyzed Domino Reactions in the synthesis of broad range of heterocycles” 33rd Annual Conference of the Indian Council of Chemists at Department of Applied Chemistry, Indian School of Mines, Dhanbadon 15th – 17th December, 2014

(5) D. Kaldhi, N. Vodnala, R. K. Linthoinganbi, S. C. Pinky Promily, C. C. Malakar “A Metal-free Domino Approach towards N-heterocycles using Easy Available Un-activated Simple Starting Materials” International Conference on Nature Inspired Initiatives in Chemical Trends (NIICT), Organic Synthesis 2016, at Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 19 – 20 September, 2016

(6) N. Vodnala, D. Kaldhi, R. K. Linthoinganbi, S. C. Pinky Promily, C. C. Malakar “Ferrites Makes it Possible via C(sp²)-H Activation: Towards the Development of Novel Routes for Indole Derivatives” International Conference on Nature Inspired Initiatives in Chemical Trends (NIICT), Organic Synthesis             2016, at Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 19 – 20 September, 2016

(7) D. Kaldhi, N. Vodnala, R. K. Linthoinganbi, S. C. Pinky Promily, C. C. Malakar “A Metal-free Approach towards C(sp)-H Functionalization of Terminal Alkynes” International Conference on Nature Inspired Initiatives in Chemical Trends (NIICT), Organic Synthesis 2016, at Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 19 – 20 September, 2016 

(8) N. Vodnala, D. Kaldhi, R. K. Linthoinganbi, S. C. Pinky Promily, C. C. Malakar “A Two-fold Un-activated C(sp²)-H Activation Approach towards Synthesis of Indole Derivatives” International Conference on Nature Inspired Initiatives in Chemical Trends (NIICT), Organic Synthesis 2016, at Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 19 – 20 September, 2016. (Received Best Poster Award)

(9) R. Gupta, N. Vodnala, D. Kaldhi, R. Gujjarappa, A. K. Kabi, S. K. Maity, R. K. Linthoinganbi, S. C.          Pinkny Promily, V. Singh, C. C. Malakar “A Surrogate Protocol for the Synthesis of Naphthoxazoles using Inexpensive Fe-catalyzed C-Arylation Approach” RAFAS 2016, at Lovely Professional University, Jalandhar, 25 – 26 November, 2016

(10) R. Gupta, N. Vodnala, D. Kaldhi, R. Gujjarappa, A. K. Kabi, S. K. Maity, C. C. Malakar “Seeking towards Novel Method for the Synthesis of Heterocycles using Easy Available Nitro-compounds” 35^th Annual Conference of the Indian Council of Chemists at Department of Chemistry, H. V. Desai College, Pune on 22 – 24 December, 2016

(11) N. Vodnala, R. Gujjarappa, A. K. Kabi, D. Kaldhi, S. K. Maity, R. Gupta, C. C. Malakar “Exploring an efficient metal-free protocol towards C-C bond cleavage for the synthesis of amide derivatives” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(12) R. Gujjarappa, N. Vodnala, D. Kaldhi, A. K. Kabi, S. K. Maity, R. Gupta, C. C. Malakar “A novel two-fold un-activated C(sp²)-H bond activation for the synthesis of isoquinolines by using amino acids as starting materials” (This poster has been selected for Best Poster Award) National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(13) S. K. Maity, R. Gujjarappa, N. Vodnala, D. Kaldhi, A. K. Kabi, S. C. PinkyPromily, R. Gupta, C. C.        Malakar “Novel C-N bond installation using C(sp²)-H bond activation towards synthesis of quinazolines” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(14) D. Kaldhi, N. Vodnala, R. Gujjrappa, A. K. Kabi, S. K. Maity, V. P. R. Kishore Putta, S. Polina, L.             Sidartha, R. Gupta, C. C. Malakar “A Greener Synthetic Approach towards Thiodiazoles and Selenodiazoles” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(15) S. K. Maity, N. Vodnala, R. Gujjarappa, A. K. Kabi, D. Kaldhi, R. Gupta, C. C. Malakar “A Metal-free C-H Activation Approach towards N-heterocycles using simple starting materials” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(16) A. K. Kabi, N. Vodnala, R. Gujjarappa, D. Kaldhi, S. K. Maity, R. Gupta, C. C. Malakar “An efficient Ni-catalyzed domino approach for the synthesis of benzimidazoles using 1,2-di-haloarene and amidine as substrates” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January, 2017

(17) R. Gujjarappa, N Vodnala, A. K. Kabi, D. Kaldhi, S. K. Maity, R. K Linthoinganbi,R. Gupta, C. C.         Malakar “Metal-catalyzed C-C bond cleavage: Exploring a rare protocol towards amide derivatives” National Symposium on Advances in Chemical Sciences at Assam University, Silchar on 11-12 January,           2017

(18) R. Gujjarappa, C. C. Malakar “An Easy Access towards 2,4 and 2,6-Functionalized Pyridines using Metal-Catalyzed Decarboxylation/Dual C(sp³)-H Activation Strategy” National Symposium on Contemporary Facets in Organic Synthesis (CFOS 2017), during 22-24 December, 2017, IIT Roorkee (This research received Best Poster award)

(19) N. Vodnala, C. C. Malakar “Seeking towards Novel Method for the Synthesis of Heterocycles using Easy Available Nitro-compounds” National Symposium on Contemporary Facets in Organic Synthesis (CFOS 2017), during 22-24 December, 2017, IIT Roorkee

(20) A. K. Kabi, C. C. Malakar “An efficient novel method for the synthesis of β-Oxo amides by ferrites” National Symposium on Contemporary Facets in Organic Synthesis (CFOS 2017), during 22-24 December, 2017, IIT Roorkee

(21) R. Gujjarappa, N. Vodnala, C. C. Malakar  “A New Strategy towards di-Functionalized Pyridines using Iron-Catalyzed Decarboxylation/Dual C(sp3)-H Activation Approach” International Conference on Emerging Trends in Chemical Sciences, during 26-28 February, 2018, Department of Chemistry, Dibrugarh University. 

 (22) N. Vodnala, R. Gujjarappa,C. C. Malakar “A Novel and Efficient Synthetic Approach towards Biologically Important N-Heterocycles using Easy Available Nitro-compounds” International Conference on Emerging Trends in Chemical Sciences, during 26-28 February, 2018, Department of Chemistry, Dibrugarh University.

(23) D. Kaldhi, C. C. Malakar “A Surrogate Protocol for the Synthesis and Functionalization of Oxazoles using Inexpensive and Easy Access Approach” International ConferenceonEmerging Trends in Chemical Sciences, during 26-28 February, 2018, Department of Chemistry, Dibrugarh University.

(24) A. K. Kabi, R. Gujjarappa, N. Vodnala, D. Kaldhi and C. C. Malakar “Gold-Catalyzed Facile Protocol Towards the Efficient Access if Azetidinyl Esters, β-Amino Esters and δ-Amino Esters Using Simple Substrates” Emerging Trends in Chemical Sciences (ETCS-2018) at Department of Chemistry, Indian Institute of Technology Indore, Indore, Madhya Pradesh, India on 12^th – 15^th July, 2019  (Received Best Poster Award)

(25) R. Gujjarappa, N. Vodnala and C. C. Malakar “Vitamin-B₃ (Niacin): An Efficient Organocatalyst for the Comprehensive Synthesis of Quinazolines using C-N Bond Formation Approach” Emerging Trends in Chemical Sciences (ETCS-2018) at Department of Chemistry, Indian Institute of Technology Indore, Indore, Madhya Pradesh, India on 12^th – 15^th July, 2019.

(26) N. Vodnala and C. C. Malakar “Copper-Catalyzed Site-Selective Oxidative C–C Bondcleavage of Simple Ketones for the Synthesis of Anilides and Paracetamol” Emerging Trends in Chemical Sciences (ETCS-2018) at Department of Chemistry, Indian Institute of Technology Indore, Indore, Madhya Pradesh, India on 12^th – 15^th July, 2019.

(27) V. P. R. K. Putta, N. Vodnala, R. Gujjarappa, U. Tyagi, P. P. Pujar and C. C. Malakar “Reagent-Controlled Divergent Synthesis of 2-Amino-1,3-Benzoxazines and 2-Amino-1,3-Benzothiazines” Emerging Trends in Chemical Sciences (ETCS-2018) at Department of Chemistry, Indian Institute of Technology Indore, Indore, Madhya Pradesh, India on 12^th – 15^th July, 2019.

(28) R. Gujjarappa, N. Vodnala, M. Kumar and C. C. Malakar “Pd-Catalyzed Decarboxylation and Dual C(sp³)−H Functionalization Protocols for the Synthesis of 2,4-Diarylpyridines” 25^th CRSI National Symposium in Chemistry (CRSI-NSC-2019) at Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India on 18^th – 21^st July, 2019.

(29) V. P. R. K. Putta, R. Gujjarappa, U. Tyagi, P. P. Pujar and C. C. Malakar “A Metal- and Base-Free Domino Protocol for the Synthesis of 1,3-Benzoselenazines, 1,3-Benzothiazines and Related Scaffolds” 25^th CRSI National Symposium in Chemistry (CRSI-NSC-2019) at Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India on 18^th – 21^st July, 2019.

(30) R. Gujjarappa, N. Vodnala, V. G. Reddy and C. C. Malakar “Niacin as a Potent Organocatalyst towards the Synthesis of Quinazolines using Nitriles as C-N Source” International Conference on Chemistry for Human Development (ICCHD-2020) at Heritage Institute of Technology, Kolkata, West Bengal, India on 9^th – 11^th January, 2020

(31) N. Vodnala, R. Gujjarappa, C. K. Hazra, D. Kaldhi, A. K. Kabi, U. Beifuss and C. C. Malakar “Copper-Catalyzed Site-Selective Oxidative C–C Bond Cleavage of Simple Ketones for the Synthesis of Anilides and Paracetamol” International Conference on Chemistry for Human Development (ICCHD-2020) at Heritage Institute of Technology, Kolkata, West Bengal, India on 9^th – 11^th January, 2020

(32) A. K. Kabi, D. Kaldhi R. Gujjarappa, N. Vodnala, N. Aljaar, C. C. Malakar “Mo(VI)-Catalyzed Synthesis of 2-Aryl-2H-Indazoles Using Pinacol Mediated Deoxygenation of Nitroaromatics” International Conference on Chemistry for Human Development (ICCHD-2020) at Heritage Institute of Technology, Kolkata, West Bengal, India on 9^th – 11^th January, 2020

(33) R. Gujjarappa, N. Vodnala, M. Kumar and C. C. Malakar “Pd-Catalyzed Decarboxylation and Dual C(sp³)−H Functionalization Protocols for the Synthesis of 2,4-Diarylpyridines” International Conference on Emerging Trends in Catalysis & Synthesis (IC-ETCS-2020) at Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India on 11^th – 12^th March, 2020

(34) A. K. Kabi, N. Vodnala, R. Gujjarappa, M. Kumar,U. Beifussand C. C. Malakar “Facile Protocols towards C2-Arylated Benzoxazoles using Fe(III)- Catalyzed C(sp²-H) Functionalization and Metal-Free Domino Approach” International Conference on Emerging Trends in Catalysis & Synthesis (IC-ETCS-2020) at Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India on 11^th – 12^th March, 2020

(35) N. Vodnala and C. C. Malakar “Reagent-Controlled Divergent Synthesis of 2-Amino-1,3Benzoxazines and 2-Amino-1,3-Benzothiazines” International Conference on Emerging Trends in Catalysis & Synthesis (IC-ETCS-2020) at Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India on 11^th – 12^th March, 2020

(36) S. Polina, V. P. R. K. Putta, R. Gujjarappa, P. P. Pujar and C. C. Malakar “An Expeditious Protocol Towards the Synthesis of N,S-Heterocycles using P(NMe₂)₃–Mediated Annulation Reactions” Virtual International Conference on Sustainable Energy and EnvironmentalTechnologies (V-ICSEET-2020) at Department of Chemistry, School of Applied Sciences, REVA University, Bengaluru, India on 2^nd – 4^th November, 2020

(37) C. C. Malakar “Catalytic Approaches towards C-C & C-Heteroatom Bond Forming Reactions” Advancements in the Molecular World: Materials and Catalysis (AMWMC-2021), NIT Surathkal, 15^th - 19^th of February 2021

(38) R. Gujjarappa and C. C. Malakar “Niacin as a Potent Organocatalyst towards the Synthesis of Quinazolines Using Nitriles as C–N Source” International Conference on 'Materials Chemistry and Catalysis (Virtual Mode) at Chemical Sciences, Tezpur University, Assam, India on 4^th – 5^th March, 2021

(39) K. Kant and C. C. Malakar “HFIP-Mediated Cyclodesulfurization Approach for the Synthesis of 2-Aminobenzoxazole and 2-Aminobenzothiazole Derivatives” 32^nd CRSI National Symposium in Chemistry (CRSI-NSC-32), BITS Pilani, Rajasthan, India on 1^st – 3^rd February, 2024

(40) C. K. Patel and C. C. Malakar “Copper-Catalyzed C (sp3)− Functionalization and Annulation of 2-Bromoaryl Oximes with Active Methylene Compounds towards Synthesis of Isoquinoline N-Oxides” 32^nd CRSI National Symposium in Chemistry (CRSI-NSC-32), BITS Pilani, Rajasthan, India on 1^st – 3^rd February, 2024

(41) Y. A. Teli and C. C. Malakar “B(OH)₃-Catalyzed Dual Friedel-Crafts Type Reaction of Anilines and Aldehydes to Access Di- or Triarylmethanes (TRAMs)” 32^nd CRSI National Symposium in Chemistry (CRSI-NSC-32), BITS Pilani, Rajasthan, India on 1^st – 3^rd February, 2024.

(42) G. Salam, C. K. Patel, K. Kant, C. C. Malakar “Reductive N-formylation of Various Nitroarenes with Novel Pd@rGO-CuFe2O4 Magnetic Nanoparticles as the Catalyst in Water” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025. (Received Best Poster Award)

(43) Ng. S. Bliss, Y. A. Teli, K. Kant, C. C. Malakar “HFIP-Mediated Dual C(Ar)-Alkylation Process Towards the Regioselective Synthesis of Triarylmethanes (TRAMs)” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(44) L. S. Devi, K. Kant, C. C. Malakar “The γ-valerolactone (GVL) as Innoxious Reaction Media for the Synthesis of 2-aryl-2H-indazoles via C-N and N-N Bond Formation under Cu(I)-Catalyzed Ligand and Base Free Conditions” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(45) R. Nongmaithem, K. Kant, C. C. Malakar “TBAI-Promoted Electrochemical Cyclization: Synthesis of Quinazolines using Cascade C-N Bond Generation” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(46)  S. Rabia, K. Kant, C. C. Malakar “HFIP-Mediated Cyclodesulfurization Approach for the Synthesis of 2-Aminobenzoxazole and 2-Aminobenzothiazole Derivatives” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(47) A. S. Devi, C. K. Patel, K. Kant, C. C. Malakar “Copper-Catalyzed C(sp³)–H Functionalization and Annulation of 2-Bromoaryl Oximes with Active Methylene Compounds towards Synthesis of Isoquinoline N-Oxides” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(48) T. A. Devi, K. Kant, C. C. Malakar “Electrochemical Cyclization-Desulfurization Approach for the Synthesis of 1,3-Benzoxazines using Cascade C-O, C-N Bonds Formation” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

(49) J. Laishram, K. Kant, C. C. Malakar “Metal- and Hazardous Reagent-Free Transamidation Process: The NH₂OH?HCl Promoted N-Formylation and N-Acylation Reaction under Solvent-Less Conditions” 3^rd National Conference on Emerging Challenges in the Frontiers of Chemical Sciences (NC-ECFCS-2025), 27^th – 28^th March, 2025.

• Associate Professor at the Department of  Chemistry, NIT Manipur (11/2022 - present)
• Assistant Professor at the Department of  Chemistry, NIT Manipur (10/2015 - 11/2022)

• Assistant Professor (on contract) at the Department of  Chemistry, NIT Jalandhar (07/2015 - 10/2015)

• Postdoctoral fellow at the Department of Inorganic and Physical Chemistry, IISc Bangalore (04/2015-07/2015)

• Senior Principal Scientist at the Department of Medicinal Chemistry, SignalChem LifeSciences Corporation Pvt. Ltd. (06/2014-02/2015)

• Postdoctoral fellow at the Department of Organic Chemistry, University of Heidelberg, Germany (12/2012-05/2014)

• Postdoctoral fellow at the Department of Organic Chemistry, University of Antwerp, Belgium (12/2011-11/2012)

• Postdoctoral fellow at the Institute Chemistry, University of Hohenheim, Stuttgart, Germany (07/2011-11/2011)

• Doctoral fellow at the Institute of Chemistry, University of Hohenheim, Stuttgart, Germany (05/2007-06/2011)

• Research Associate at the Department of Organic Chemistry, Ludwig Maximilians University (LMU) Munich, Germany (07/2006-04/2007)

• M.Sc Thesis at Indian Institute of Technology Kanpur (IIT K), India (2006)

• M.Sc (Chemistry) at Indian Institute of Technology Kanpur (IIT K), India (2004-2006)

• M.Sc (Chemistry) at Banaras Hindu University (BHU) (2003-2004)

• B.Sc (Chemistry, Hons) at Vidyasagar University (Panskura Banamali College) (2000-2003)

 Teaching Information:

   Present:

• M.Sc course: Organic Reaction Mechanism at NIT Manipur  (10/2015 - present)
• M.Sc course: Application of Spectroscopy (Organic Section) at NIT Manipur (10/2015 - present)
• M.Sc course: Principle in Organic Chemistry at NIT Manipur (10/2015 - present)
• M.Sc course: Concepts in Organic Synthesis at NIT Manipur (10/2015 - present)
• M.Sc course: Organic Chemistry Laboratory at NIT Manipur (01/2016 - present)
• B.Tech course: Engineering Chemistry (Organic Section) 

   Past:

• Laboratory courses for UG students at University of Hohenheim, Stuttgart, Germany (2007 -  

          2011)

• B.Tech Chemistry courses (Organic Section) at NIT Jalandhar (07/2015 - 10/2015)

• B.Tech: Environmental Science and Technology (EST) at NIT Jalandhar (07/2015 - 10/2015)

• B.Tech Chemistry laboratory courses at NIT Jalandhar (07/2015 - 10/2015)

• PhD course work: Principal of Instrumental Method of Analysis (PIMA) at NIT Jalandhar (07/2015 - 10/2015).

Mentorship Experiences:

• Ph.D Supervision (Completed): 

(1) Dr. Nagaraju Vodnala (Enrolment No.: 16PCH002), Title of the Thesis: Development of Novel Catalytic Approaches towards Synthesis and Functionalization of Biologically Valued N- Heterocycles. Thesis Defense:  18/09/2020. 

 (2) Dr. Dhananjaya Kaldhi (Enrolment No.: 16PCH001), Title of the Thesis: Efficient Catalytic transformation towards Important N-Heterocycles and conjugated 1,3-Diynes and Enynes. Thesis Defense: 05/12/2021.

(3) Dr. Raghuram Gujjarappa (Enrolment No.: 16402003), Title of the Thesis: Development of Divergent Organic Transformations towards the Synthesis and Functionalization of Bioactive Molecules" Thesis Defense: 31/01/2022. 

(4) Dr. Arup Kumar Kabi (Enrolment number: 16402001): Title of the Thesis: "Synthesis and Functionalization of Biologically Active Novel N-heterocycles towards Greener Horizon". Thesis Defense: 02/09/2022.  

(5) Dr. Elangbam Pinky Devi (Enrolment number: 18402002): Title of the Thesis: "Development of Catalytic Systems for C-N Bond Forming Transformations and Oxidation of Alkynes” Thesis Defense: 18/05/2024.     

(6) Dr. Laimujam Sidartha Singh (Enrolment number: 19402003): Title of the Thesis: "Development of Catalytic Systems for C-N & N-N Bond Forming Transformations and Organocatalyzed-Aerobic Oxidation of Arylboronic Acids” Thesis Defense: 20/08/2024.

(7) Ms. Reetu (Enrolment No. 20402007): Title of the Thesis: “Development of Strategies towards the Synthesis of Iodo-Derivatives: Impacts of the Hetero- and Carbocyclic Moieties”, Thesis Defense on 11^th March, 2025.  

(8) Mr. Chandresh K. Patel (Enrolment No. 19402001): Title of the Thesis: “Development of Cascade C-N Bond Generation Strategies: Application in the Synthesis of Nitrogen Containing Cyclic and Acyclic Molecules”, Thesis Defense on 04^th March, 2025. 

(9) Mr. Yaqoob A. Teli (Enrolment No. 21402005): Title of the Thesis: “Development of homogeneous and heterogeneous catalysts in C-C bond forming reactions”, Submitted on February 2025. 

(10) Mr. Abhisek Panwar (Enrolment No. 20402004): Title of the Thesis: “Iron(III)-Chelators and Heterobimetallic Systems as the Novel Approach for Targeted Chemotherapy and Photocytotoxicity”, Submitted on 14.05.2025. 

• Ph.D Supervision (On-going): 

          Currently 6 (six) scholars are pursuing Ph.D under my supervision.

• PG Supervision (Completed) – Supervised 38 Master’s Thesis since 2015.
• PG Supervision (On-going): Currently 2 (two) students are pursuing M.Sc project under my supervision.
  

Placement of M.Sc Students:

• The M.Sc students are placed for Ph.D program in reputed national institutions like IISERs, IITs, and NITs and in several international institutions in USA, Germany, Poland, South Korea and Taiwan.

Placement of Ph.D Scholars:

• The Ph.D scholars are placed for postdoctoral research in several reputed national and international institutions such as IIT Delhi; Technion-The Israel Institute of Technology, Israel; Southern Methodist University, Texas, USA; University of Twente, Netherlands; University of Warsaw, Poland; Harbin Institute of Technology; Shenzhen, China; Saint-Jérôme University Campus, France).
• The Ph.D scholars are also placed in Pharma companies such as Aurobindo Pharma Ltd., Hyderabad and Aztec Technologies, Hyderabad.

National & International Collaborations:

• National Institute of Pharmaceutical Education and Research (NIPER) Kolkata
• Central University of Punjab, Bhatinda
  
• Institute of Chemical Technology (ICT) Bhubaneswar
  
• Indian Institute of Technology (IIT) Delhi
  
• Indian Institute of Technology (IIT) Guwahati
  
• Indian Institute of Technology (IIT) Bombay
  
• Birla Institute of Technology & Science (BITS) Pilani
  
• CHRIST University, Bangalore
  
• Pandit Deendayal Petroleum University, Gandhinagar
  
• National Institute of Technology (NIT) Jalandhar
• National Institute of Technology (NIT) Jamshedpur
  
• National Institute of Science Education and Research (NISER) Bhubaneswar
  
• Technion - Israel Institute of Technology, Israel
  
• RMIT University, Melbourne, Australia
  
• The Hashemite University, Zarqa, Jordan
  
• Korea Advanced Institute of Science & Technology (KAIST), South Korea
  
• King Abdullah University of Science and Technology, KAUST Catalysis Center, Saudi Arabia
  
• King Saud University, Saudi Arabia
• University of Hohenheim, Stuttgart, Germany
  
• The Pennsylvania State University, USA
• Karlsruhe Institute of Technology, Germany
  
• The University of Warsaw, Poland
  

Research Interest:

• C-H activation: carbon-carbon and carbon-hetero atom bond forming reactions

• Asymmetric catalysis, transition-metal catalysis and organocatalysis

• Frustrated Lewis Pairs

• Cooperative dual catalysis and “release and catch” catalysis

• Synthesis and application of novel ligands in asymmetric catalysis

• Drug discovery research and medicinal chemistry

• Bioactive natural product synthesis and chemistry of heterocycles

• The development of new sustainable and atom-economy chemical transformations, cascade reactions, domino reactions, and multi-component reactions

 

Funds Received to Conduct R&D Activities:

 (1) Funding Agency:  Department of Science and Technology, Govt. of India - SERB                         Duration: 3 years (2016 - 2019), Fund:  Rs. 38,84,000 /-.                                                                               Project Title: "Synthesis and Decoration of Drug-like Molecules using Transition Metal-Catalyzed C(sp²)–H/C(sp³)–H Bond Activation Approach" (Role: PI)

(2) Funding Agency: Department of Science and Technology, Govt. of India - SERB                           Duration: 3 years (2020 - 2023), Fund: Rs. 35,77,332 /-,                                                                          Project Title: "Investigation on Metal-Free Approaches towards C-C and C-Heteroatom Bond Formation for the Synthesis of Carbocycles and Heterocycles" (Role: PI)

(3) Funding Agency: MoE-STARS, STARS-2, Govt. of India,                                                                  Duration: 3 years (2023 - 2026), Fund: Rs. 15,94,000 /-.                                                                         Project Title: "Investigation of Novel Therapeutic Compounds for Inhibitors of the Protein Kinase Family to Treat Cancer: Synthesis and Evaluation of Biological Activity" (Role: PI)

(4) Funding Agency: SERB, Govt. of India, Duration: 3 years (2022 - 2025), Fund: Rs. 20,18,362 /-    Project Title: Computational studies on investigation of the potential role of metalbased compounds as the inhibitors of SARS-CoV-2 as well as other aggressive mutant strains of SARS-CoV-2. (Role: Co-PI)

(5) Funding Agency: (ICMR, Govt. of India), Duration: 3 years (2022 - 2025), Fund: Rs. 25,62,450 /-  Project Title: Novel Cobalt(III)-based bio reductive prodrug modelling for hypoxia selective chemotherapeutic steering of hypoxia-inducible factors (HIF) as an alternative source of treatment stratagem for breast cancer. (Role: Co-PI)

Funds Received to Conduct Academic Program:

(6) Awarded Fund (Rs. 3,00,000 /-), sponsored by AICTE-ATAL, Govt. of India to conduct the program on Leadership Excellence & Capacity Building (Role: PI)

(7) Awarded Fund (Rs. 5,44,000 /-), sponsored by GIAN (Global Initiative of Academic Network) – MHRD, Govt. of India.                                                                                                                                 Course Title: “Organic Synthesis towards Greener Horizons: Challenges and Scope” (2017).               Course coordinator: Dr. Chandi Charan Malakar                                                                                     Foreign Faculty: Prof. Dr. Uwe Beifuss, Institute of Chemistry, University of Hohenheim, Stuttgart, Germany.

(8) Awarded Fund (Rs. 5,44,000 /-), sponsored by GIAN (Global Initiative of Academic Network) – MHRD, Govt. of India (2019).                                                                                                                      Course Title: “Novel Platform on Organocatalysis – Since & Then”                                                       Course coordinator: Dr. Chandi Charan Malakar                                                                                    Foreign Faculty: Prof. Dr. Rene Wilhelm, Department of Chemistry, University of Paderborn, Germany.

(9)  Awarded Fund (Rs. 5,44,000 /-),sponsored by GIAN (Global Initiative of Academic Network) – MHRD, Govt. of India (2019)                                                                                                                       Course Title: “Diverse Application of Modern Stereoselective Synthesis - Where Now ?”                                 Course coordinator: Dr. Chandi Charan Malakar                                                                                    Foreign Faculty: Prof. Dr. Ilan Marek, Department of Chemistry, Technion – Israel Institute of Technology, Israel.